Towards precision medicine in colon cancer: biomarkers, tumour microenvironment and microbiota
Publications CIB-CSIC
Scientific Article 2021. Jaén M, Bartolomé RA, Aizpurua C, Martin-Regalado Á, Imbaud JI, Casal JI. Inhibition of Liver Metastasis in Colorectal Cancer by Targeting IL-13/IL13Rα2 Binding Site with Specific Monoclonal Antibodies. Cancers (Basel). 2021 Apr 6;13(7):1731. doi: 10.3390/cancers13071731. PMID: 33917458; PMCID: PMC8038733.
Scientific Article 2021. Bartolomé RA, Robles J, Martin-Regalado Á, Pintado-Berninches L, Burdiel M, Jaén M, Aizpurúa C, Imbaud JI, Casal JI. CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers. Mol Oncol. 2021 Jul;15(7):1849-1865. doi: 10.1002/1878-0261.12947. Epub 2021 May 2. PMID: 33715292; PMCID: PMC8253092.
Scientific Article 2020. Bartolomé RA, Pintado-Berninches L, Jaén M, de Los Ríos V, Imbaud JI, Casal JI. SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166. Oncogene. 2020 Sep;39(38):6085-6098. doi: 10.1038/s41388-020-01419-4. Epub 2020 Aug 15. PMID: 32801337.
Scientific Article 2020. Bartolomé RA, Martín-Regalado Á, Jaén M, Zannikou M, Zhang P, de Los Ríos V, Balyasnikova IV, Casal JI. Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells. Cancers (Basel). 2020 Feb 21;12(2):500. doi: 10.3390/cancers12020500. PMID: 32098194; PMCID: PMC7072372.
Scientific Article 2020. Escudero-Paniagua B, Bartolomé RA, Rodríguez S, De Los Ríos V, Pintado L, Jaén M, Lafarga M, Fernández-Aceñero MJ, Casal JI. PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway. Carcinogenesis. 2020 Apr 22;41(2):203-213. doi: 10.1093/carcin/bgz093. PMID: 31095674.
Scientific Article 2018. Bartolomé RA, Jaén M, Casal JI. An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer. Br J Cancer. 2018 Oct;119(8):940-949. doi: 10.1038/s41416-018-0259-7. Epub 2018 Oct 15. PMID: 30318506; PMCID: PMC6203792.
Scientific Article 2018. Torres S, García-Palmero I, Marín-Vicente C, Bartolomé RA, Calviño E, Fernández-Aceñero MJ, Casal JI. Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer. J Proteome Res. 2018 Jan 5;17(1):252-264. doi: 10.1021/acs.jproteome.7b00548. Epub 2017 Nov 21. PMID: 29131639.
Scientific Article 2018. Bartolomé RA, Aizpurua C, Jaén M, Torres S, Calviño E, Imbaud JI, Casal JI. Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis. Clin Cancer Res. 2018 Jan 15;24(2):433-444. doi: 10.1158/1078-0432.CCR-17-1444. Epub 2017 Sep 15. PMID: 28916526.
Scientific Article 2017. Torres S, Garcia-Palmero I, Bartolomé RA, Fernandez-Aceñero MJ, Molina E, Calviño E, Segura MF, Casal JI. Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis. J Pathol. 2017 May;242(1):39-51. doi: 10.1002/path.4874. Epub 2017 Mar 7. PMID: 28054337.